The PCI_COM driver in Windows typically refers to a device driver used for communication between a PC's PCI (Peripheral Component Interconnect) bus and serial communication hardware, such as a serial port (RS-232, RS-485), or other serial interfaces that connect to the computer through a PCI expansion card. The "COM" part often suggests that the device is functioning as a COM port, which is a communication port for serial devices.
The PCI_COM driver could be associated with a number of devices, such as: